Research & Guides
Honest, research-backed writing on the supplements and protocols that actually help.
The 6 Best Supplements for Hashimoto’s (Backed by Research, Not Hype)
A pharmacist-style breakdown of the supplements with real evidence behind them for Hashimoto’s thyroiditis — selenium, magnesium, vitamin D, zinc, iron, and B12 — plus the popular ones that waste your money.
Leaky Gut Supplements: What Actually Repairs the Gut Lining
L-glutamine, zinc-carnosine, butyrate, and the right probiotic strains have real mechanisms behind them for intestinal permeability. Here is how to build a gut-repair stack without wasting money on the rest.
Best Supplements for Eczema: The Gut-Skin Connection Explained
Eczema is inflammation you can see on the outside, often driven by what is happening on the inside. Here are the supplements with real evidence — omega-3s, vitamin D, zinc, and probiotics — and how the gut-skin axis ties them together.
Best Supplements for Fibromyalgia & Chronic Fatigue: An Energy-First Protocol
Fibromyalgia and ME/CFS share a common thread — cells that struggle to make energy. This protocol focuses on the mitochondrial supplements with the best evidence: magnesium malate, CoQ10, D-ribose, and methylated B vitamins.
Histamine Intolerance Supplements: DAO, Quercetin & What Actually Works
If aged cheese, leftovers, or a glass of wine trigger flushing, headaches, and a racing heart, low DAO may be the cause. Here are the supplements that genuinely help with histamine intolerance and MCAS — and the probiotic mistake that makes it worse.
Gluten and Hashimoto’s: Does Going Gluten-Free Actually Lower Antibodies?
The gluten-free advice for Hashimoto’s is everywhere — but what does the evidence actually show? Here is the molecular-mimicry theory, what the studies found, and how to test it without giving up bread forever for nothing.
Seed vs Visbiome vs Florastor: Which Probiotic Is Right for Your Gut?
Three of the most recommended probiotics work in completely different ways. This head-to-head breaks down the strains, the evidence, and exactly who each one is best for — so you stop guessing in the supplement aisle.
The Elimination Diet for Eczema: A Step-by-Step Guide to Finding Your Triggers
Food is not the cause of every eczema flare — but for some people it is a major one. Here is how to run a proper elimination diet to identify your triggers without guesswork, crash dieting, or nutritional gaps.
CoQ10 vs Ubiquinol: Which Form Is Better for Chronic Fatigue?
Ubiquinol is marketed as the “superior, pre-activated” CoQ10 — and it costs more. But is it actually better for fibromyalgia and chronic fatigue? Here is what the absorption science really says, and how to choose without overpaying.
The Low-Histamine Diet: Foods to Avoid, Foods to Enjoy, and How to Start
A practical beginner’s guide to the low-histamine diet — why fresh food is everything, the worst high-histamine offenders, the safest foods to build meals around, and how to start without making yourself miserable.
Still Tired on Levothyroxine? Why Your Hypothyroid Symptoms Persist
Your TSH is “normal” but you are still exhausted, foggy, and cold. You are not imagining it. Here are the real reasons hypothyroid symptoms persist on levothyroxine — from T4-to-T3 conversion to the deficiencies your labs miss.
IBS vs IBD: What’s the Difference (and Why It Changes Everything)
IBS and IBD sound almost identical and share symptoms — but they are fundamentally different conditions with very different stakes. Here is how to tell them apart and why the distinction shapes your entire treatment and supplement approach.
Vitamin D for Psoriasis: How Much to Take and Why It Helps
Vitamin D is one of the few supplements with a direct mechanism in psoriasis — it is literally how some prescription creams work. Here is what the research shows, the blood level to aim for, and how to dose it safely.
Magnesium Glycinate vs Malate: Which Is Better for Fibromyalgia?
Both forms of magnesium help with fibromyalgia — but they shine at different jobs. Glycinate calms and aids sleep; malate targets pain and daytime energy. Here is how to choose, or why you might use both.
Quercetin for Histamine Intolerance: Dose, Timing, and How It Works
Quercetin is the natural mast cell stabilizer at the heart of most histamine protocols — but plain quercetin barely absorbs. Here is how it works, the dose that matters, and why the form you buy makes or breaks it.
Thyroid Labs Explained: TSH, Free T4, Free T3, and Antibodies
A single TSH test rarely tells the whole story. Here is what each thyroid lab actually measures — TSH, free T4, free T3, reverse T3, and TPO antibodies — and which ones to ask for so you can finally understand your results.
Digestive Enzymes: Do They Actually Work, and Who Needs Them?
Digestive enzyme supplements promise to fix bloating and help you break down food — but do they work, or is it hype? Here is what enzymes actually do, who genuinely benefits, and how to take them so they help.
How to Choose the Best Moisturizer for Eczema (and Use It Right)
The right moisturizer is the single most important part of eczema care — more than any supplement. Here is what ingredients actually repair the skin barrier, what to avoid, and the timing trick that doubles the benefit.
The Best Sleep Supplements for Fibromyalgia (and Why Sleep Comes First)
Unrefreshing sleep is at the core of fibromyalgia — fix it and pain and fatigue often improve too. Here are the sleep supplements with the best rationale, from magnesium glycinate to glycine, and how to use them.
MCAS Symptoms Checklist: 20+ Signs of Mast Cell Activation
A clear, system-by-system checklist of mast cell activation syndrome symptoms — what they feel like, why they cluster, and when to seek a proper evaluation.
Myo-Inositol for Thyroid: Does It Help Hashimoto’s?
Myo-inositol is one of the few supplements with real trial data in Hashimoto’s. Here is what the research shows about TSH, antibodies, and who it actually helps.
Does Collagen Heal Your Gut? What the Evidence Actually Says
Collagen is marketed everywhere for “gut healing.” Here is what the science really supports, where the hype outruns the data, and what to use instead.
Topical Steroid Alternatives for Eczema That Actually Work
Worried about steroid creams? Here are the evidence-based alternatives and add-ons — from barrier repair to diet and supplements — that genuinely calm eczema.
Post-Exertional Malaise: Why You Crash After Activity
If light activity leaves you wiped out for days, you may have post-exertional malaise. Here is what PEM is, why pushing through backfires, and how to manage it.
Vitamin B6, Copper, and DAO: The Histamine Connection
DAO is the enzyme that clears dietary histamine — and it depends on vitamin B6 and copper to work. Here is how these nutrients fit into a histamine plan.
The Adrenal-Thyroid Connection: Cortisol, Stress & Hashimoto’s
Chronic stress and cortisol can blunt thyroid function and worsen Hashimoto’s. Here is how the adrenal-thyroid link works — and what actually helps.
The Low-FODMAP Diet: A Practical Guide for IBS
The low-FODMAP diet is the most evidence-backed dietary approach for IBS. Here is how the three phases work, what to eat, and how to do it without over-restricting.
Fish Oil for Skin: Does Omega-3 Help Eczema & Psoriasis?
Omega-3 fish oil is one of the most studied supplements for inflammatory skin. Here is what the evidence shows for eczema and psoriasis, and how to use it well.
D-Ribose for Energy: Does It Help Fibromyalgia & Fatigue?
D-ribose is marketed for energy and fibromyalgia. Here is what the science actually shows, who might benefit, and how it compares to other fatigue supplements.
DAO Enzyme Supplements Compared: Which One Actually Works?
DAO supplements help break down dietary histamine — but they are not all equal. Here is how they differ, what to look for, and how to use them correctly.